‘Latent’ Tuberculosis? It’s Not That Common, Experts Find
20 SEP - Active infections kill 4,000 people a day worldwide, more than AIDS does. But the notion that a quarter of the global population harbors silent tuberculosis is “a fundamental misunderstanding.”
The devastating effect of world's biggest ever flu outbreak
20 SEP - New research into the the world’s worst ever flu pandemic reveals the toll the illness wrought on ordinary people still suffering the devastating effects of the First World War.
WHO Global Tuberculosis Report
19 SEP - WHO has published a global TB report every year since 1997. This 2018 edition is published in the lead up to the UN high-level meeting on TB.
World Health Organization Early Warning, Alert, and Response System
Ahead of Print November 2018 - The Early Warning, Alert, and Response System (EWARS) is a web-based system and mobile application for outbreak detection and response in emergency settings. EWARS provided timely information on epidemic-potential diseases among >700,000 Rohingya refugees across settlements. EWARS helped in targeting new measles vaccination campaigns and detecting outbreaks of acute jaundice syndrome.
Opinion: Our lack of pandemic preparedness could prove deadly
SEP 19 - Policymakers need to pay much closer attention to the threats that could be posed by biologically engineered pathogens. There are still no licensed vaccines for most of the deadly viral pathogens that have occurred naturally in the past 40 years. That includes HIV, West Nile, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). A pathogen that combined the lethality of any of these diseases with the ability to spread like influenza could cause extraordinary illness and mortality
Lessons from the latest Ebola outbreak in the DRC
19 SEP - In this guest commentary, Philip A. Lederer, MD, assistant professor of medicine at Boston University School of Medicine and an infectious disease physician at Boston Medical Center, discusses lessons that the global health community must learn from Ebola virus outbreaks.
Tuberculosis update 2018 from A/Prof Anna Ralph
19 SEP - New(ish) WHO strategy and targets, New terminology, New terminology etc.
Better than DEET Repellent Compounds Derived from Coconut Oil
19 SEP - N,N-Diethyl-meta-toluamide (DEET), the most effective and long-lasting repellent currently available commercially, has long been considered the gold standard in insect repellents, but with reported human health issues, particularly for infants and pregnant women. In the present study, we report fatty acids derived from coconut oil which are novel, inexpensive and highly efficacious repellant compounds. These coconut fatty acids are active against a broad array of blood-sucking arthropods including biting flies, ticks, bed bugs and mosquitoes. The medium-chain length fatty acids from C8:0 to C12:0 were found to exhibit the predominant repellent activity. In laboratory bioassays, these fatty acids repelled biting flies and bed bugs for two weeks after application, and ticks for one week. Repellency was stronger and with longer residual activity than that of DEET. In addition, repellency was also found against mosquitoes. An aqueous starch-based formulation containing natural coconut fatty acids was also prepared and shown to protect pastured cattle from biting flies up to 96-hours in the hot summer, which, to our knowledge, is the longest protection provided by a natural repellent product studied to date.
TB Alliance and Liverpool School of Tropical Medicine Collaborate to Develop New TB Therapies
19 SEP - New partnership supported by Medical Research Council to research drug regimens to fight drug-resistant tuberculosis
New Vaccine Technologies to Combat Outbreak Situations
19 SEP - Susanne Rauch, Edith Jasny, Kim E. Schmidt and Benjamin Petsch
Established methods for the identification of new vaccine candidates are no longer sufficient to ensure global protection. Hence, new vaccine technologies able to achieve rapid development as well as large scale production are of pivotal importance. This review will discuss viral vector and nucleic acid-based vaccines (DNA and mRNA vaccines) as new approaches that might be able to tackle these challenges to global health.