PNG and the Republic of Indonesia for the Micro-Elimination of tuberculosis - PRIME-TB


Laboratory Strengthening


Indonesia and Papua New Guinea (PNG)

What this project will achieve:

Tuberculosis (TB) remains endemic in our region and is the second leading major cause of death in both Indonesia and PNG.

At the end of this project, there will be four knowledge hubs in Yogyakarta and Mimika in Indonesia, and Port Moresby and Daru in PNG that can pilot and scale up successful innovations in TB case detection and models of care, and conduct enhanced molecular and epidemiological surveillance, supporting the micro-elimination of TB in these areas.

How this project will do it:

Prime-TB hubs will be established in existing health facilities in each location. The hubs will be integrated into the Ministry of Health services.

The hubs will also serve as Centres of Excellence, with resources to mentor TB health workers from across PNG and Indonesia on effective clinical management of TB patients.

Using a continuous quality improvement approach, PRIME-TB will pilot evidence-based TB treatments and innovations to determine their suitability for scaling up to other regions. Pilots will focus on active TB case finding, access to patient-centred care, and access to innovative TB treatments. Adapted training, toolkits, resources and learning networks for healthcare workers on TB micro-elimination will be developed and rolled out to support successful pilots.

Within the target cities, PRIME-TB project staff will use peer education and counselling to raise community awareness of TB health services and generate demand for services that address barriers to accessing care including gender-specific barriers. In addition, the program will work with public health leaders to identify approaches to sustain a concerted effort for TB eradication.

How the project has responded to COVID-19:

GeneXpert machines are regularly used to detect the presence of TB in Papua New Guinea and Indonesia. Individuals with COVID-19 or TB may present with similar respiratory symptoms. PRIME-TB has received additional funds to help these countries use GeneXpert machines to test individuals for both COVID-19 and TB simultaneously, in accordance with World Health Organization guidance.

Lead implementing partner:


  • PNG and Indonesia Ministries of Health and local governments
  • Menzies School of Health Research
  • Papua New Guinea Institute of Medical Research
  • Centre for Tropical Medicine at Universitas Gadja Mada, Indonesia
  • James Cook University



For more information:

Philipp DuCros, Burnet Institute