A new vaccine to prevent dengue may be on the horizon. And health officials say it's desperately needed. The World Health Organization this year listed dengue as one of the top 10 threats to global health. The mosquito-borne disease is a growing threat for several reasons. First, the sheer number of dengue cases has been increasing dramatically in recent years. The WHO says there's been a 30-fold increase in infections since 1970. Last year nearly 100 million people came down with the disease. s Derek Wallace, who leads the Takeda Pharmaceutical Company think they're very close to having a marketable vaccine that could dramatically reduce the number of cases of the mosquito-borne disease. "We're thrilled with the results," Wallace says, about a large-scale study of a vaccine they're calling TAK-003. Staring in 2016, Takeda enrolled 20,000 people between the ages of 4 and 16 in a study of TAK-003. The vaccinations occurred at 26 sites in seven dengue-endemic countries. In results just published in the New England Journal of Medicine, Wallace and his colleagues found TAK-003 to be 80% effective in preventing participants from getting dengue and 95% effective in preventing cases of severe dengue.